Laboratory Associate Biochemistry

CK QLS are looking for a Laboratory Associate Biochemistry/ Research Associate (80-100%) to be based in Aargau canton.

The Company 

The company is a rapidly growing biotech company focusing on solving structures of membrane protein drug targets (e.g. GPCRs, ion-channels and transporters) for the discovery and optimization of next-generation medicines. Based on a unique platform for membrane protein expression, purification and engineering, and preferential access to synchrotron and free electron laser (SLS/SwissFEL) beamlines for X-ray analysis and cryo-EM facilities, they characterize the interaction of small molecules and biotherapeutics with drug targets in time to impact the discovery of novel therapeutics. 

The Position:

You will be part of an interdisciplinary team of researchers working on the company proprietary, as well as partnered projects within a highly collaborative international environment. The successful candidate will perform protein biochemistry to provide high quality membrane protein samples for structural and biophysical studies.  

Key Tasks and Responsibilities:

The successful candidate will be expected to work within a dynamic team that values transparency, integrity, reliability, and a passion for science to create benefits for the patients. 

Key Duties Include: 

• Purification of membrane proteins using a variety of chromatographic methods including affinity, ion exchange and size exclusion chromatography.
• Monitoring of protein quality using analytical methods including fluorescence-size exclusion chromatography, SDS-PAGE, Western blotting, and in-gel fluorescence.
• Documentation of laboratory work and participation in data analysis, use of electronic lab note book for data recording.
• Laboratory organization and maintenance of supplies and equipment.
• Contribution to scientific research on membrane proteins for drug discovery within an experienced team.

Your Qualifications:

• Applicants should have an apprenticeship as laboratory technician and at least 5 years hands-on experience with protein purification and standard protein analytical techniques.
• Previous experience with membrane protein purification is required.
• Profound experience with HPLC and Äkta instrument handling is required.
• Previous experience with membrane protein biochemistry and work experience in industry is a plus.
• Excellent communication skills and fluency in English are essential, knowledge of German would be advantageous.

Benefits:

• You will be working for an innovative company aiming to discover new generation medicine.
• You will be working with state-of-art technologies.
• You will be working in a supportive and dynamic team.
• Share options bonus.

Please quote job reference 102248 in all correspondence.