Senior Scientific Associate ADQC / Analytical Development & Technologies

  • Salary: Competitive
  • REF Number: v-99451
  • Consultant: Adrien Guimard
  • Contact: +41 (0) 800 106106
  • Date Published: 15.05.2024
  • Industry: Pharmaceutical
  • Location: Basel, Switzerland
  • Functional Expertise:

QLS are recruiting for a Senior Scientific Associate Analytical Development & Technologies to join an innovative pharmaceutical company based in Basel on a contract basis for 12 months.

 

RESPONSIBILITIES AND TASKS:

The main responsibility of the Analytical Development and Technologies (ADT) within ADQC is the development, optimization, verification and conduct of analytical methods for a broad range of techniques such as e.g.:

  • HPLC and UPLC and GC with different detection modality (e.g. PDA, FLD, MS).
  • HR-MS for assay, purity, related substances, and mutagenic and carcinogenic impurities determination.
  • IC for cation and anion determination.
  • NMR for structure confirmation/elucidation and for assay and impurity determination.
  • Various spectroscopical techniques: FT-IR, Raman, UV/Vis, Color/turbidity of solution.
  • Coulometric/Volumetric Karl Fischer for water determination.
  • Particle size distribution and shape analysis by laser diffraction and optical microscopy.
  • Techniques characterizing APIs with low solubility (e.g. in Amorphous Solid Dispersion).
  • Dissolution, Content Uniformity, Content and Related Substances.
 

Following Responsibilities:

  • Development, assessment, optimization, and application of analytical methods applying analytical techniques mentioned above.
  • Conduct of release, retest, stability studies, transfer and (pre-) validation analyses.
  • Write-up and review of analytical method protocols, reports (e.g. for development).
  • Planning and execution of experiments for method development, assessment, optimization, and application.
  • Planning, execution and reporting of forced degradation studies.
  • Participation in meetings at intra- and inter-departmental level (e.g., CMC, subject specific working groups).
  • Proper documentation of all analytical activities through compilation of all analytical testing records (e.g., notebooks, raw data hardcopies).
  • Interpretation and documentation of analytical data including results.
  • Drafting and review of CoAs and/or Analytical results sheet and SOPs.
  • Training of Laboratory personnel.
  • Independently designs and executes projects or experiments with hands on involvement.
 

REQUIRED QUALIFICATIONS AND EXPERIENCE:

  • Apprenticeship-, College-, or university-degree or equivalent education in the field of chemistry, biology, biochemistry, pharmacy, or chemical engineering.
  • Ideal education and experience: Apprenticeship plus 6-10 years, BSc plus 4-8 years or MSc plus 3-5 years.
  • Good knowledge of analytical chemistry with advanced knowledge of sample preparation, analytical instrumentation techniques especially in chromatography, mass spectrometry, and spectroscopy. Good troubleshooting skills for analytical instrumentation.
  • High flexibility, advanced communication, time-management and team-working skills and basic knowledge of QC or GMP.
  • Ability to work independently and to take initiative. Life-long learning mindset and strong sense of accountability.
  • Proficient in English.

Apply:

Please could you send any correspondence in English. Please quote job reference 99451 in all correspondence. 

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