Scientist Antibody

Scientist, Antibody

Join a cutting-edge, clinical-stage precision immuno-oncology company focused on developing breakthrough treatments for solid tumors and hematological malignancies. This full-time, permanent role offers the opportunity to contribute to the advancement of a leading program developed by renowned scientists from Dana Farber, MGH, the Broad, and MIT. With over $120M raised from top-tier investors, the company is driving its clinical pipeline forward while expanding and validating novel therapeutic programs.

Job Summary:

We are seeking a talented scientist with expertise in antibody discovery, engineering, and characterization. Reporting to the Senior Director of Antibodies, the successful candidate will play a pivotal role in discovering and optimizing therapeutic antibodies. This is a primarily lab-based position, with opportunities to collaborate on project teams, interact with CRO partners, and contribute to strategic decision-making.

Key Responsibilities:

• Design, construct, and screen antibody libraries to identify or optimize antibodies with desired properties.
• Conduct biophysical characterization of antibodies.
• Collaborate closely with the Biology group to accelerate program advancement.
• Present and communicate research findings in group and project meetings.
• Maintain thorough documentation of experimental work in electronic lab notebooks.

Qualifications & Education Requirements:

• BS with 5+ years, MS with 3+ years, or PhD in a relevant field (title will be based on experience).
• Proven hands-on experience with yeast display and/or phage display.
• Expertise in antibody affinity maturation, humanization, and related techniques.
• Skilled in antibody biophysical characterization methods such as ELISA, binding kinetics (Octet/SPR), flow cytometry, DSF, and more.
• Experience with alternative antibody formats like single-domain or bispecific antibodies is a plus.
• Strong knowledge of therapeutic antibody development.
• Ability to work independently, designing, executing, and troubleshooting experiments with minimal supervision.
• A collaborative team player with excellent verbal and written communication skills, capable of thriving in a fast-paced environment.

Additional Information:

• Candidates must have the right to work in the U.S. and be available to start immediately.

Apply:

Please quote job reference 107530 in all correspondence.