Principal Scientist
CK Group are recruiting for an experienced and dynamic Scientist, at either Senior/ Principal level, to join an early-stage biotechnology start-up, based in Oxford, on a permanent basis.
The Company:
Our client is an early-stage biotechnology start up, combining artificial intelligence (AI), and advanced high-throughput TCR screening techniques to revolutionise the treatment of solid cancers.
Location:
Oxford.
The Role:
To lead the in vivo and in vitro validation of T-cell engagers, and help drive forward the development of TCR engineering and processes.
Responsibilities:
- To perform high-throughput TCR display methods by purifying recombinant TCRs.
- Carry out protein characterisation (expression, purification and biophysical analysis).
- Design and characterise TCRs for disease targets.
- Oversee lab protocols and technical documents.
- To be hands-on in the lab and manage tissue culture preparations.
- Skills in data analysis (using software R) for Next Gen Sequencing analysis - desirable.
Your Background:
- PhD qualified (biochemistry, immunology, cell biology) plus strong laboratory experience (academia and industry).
- Experience in in vivo and in vitro validation of T-cell engagers (TCEs).
- Experience in Investigational New Drug (IND-enabling/ approval) - ESSENTIAL.
- Expertise in cell and immunological assays (flow cytometry, ELISA) with knowledge around cloning and PCR.
- Strong background in protein characterisation and biophysical characterisation.
Benefits:
Competitive salary, option for home working (as per project demands), stock options.
Apply:
It is essential that applicants hold entitlement to work in the UK. Please quote job reference 141 244 in all correspondence.
If this position isn't suitable but you are looking for a new role, or if you are interested in seeing what opportunities are out there, head over to our LinkedIn page (cka-group) and follow us to see our latest jobs and company news.
INDCP