Senior Scientist - In Vitro Pharmacology

  • Salary: $150,000
  • REF Number: 00054215
  • Consultant: Hannah Oakley
  • Contact: 01246 457711
  • Date Published: 11.08.2022
  • Closed Date: 29.09.2022
  • Industry: Biotechnology
  • Location: Waltham, MA, USA East Coast (Boston)
  • Functional Expertise: Research & Development

CK Group is seeking a dynamic scientist /senior scientist to join our client who are based in Waltham, MA on a full time basis.

The Company:

Our client are a growing clinical stage biopharmaceutical company, established to pioneer the next generation of therapies in the oncology and autoimmune space.

Job Summary:

The successful candidate will join an In vitro Pharmacology group to lead early-stage studies and programs with investigative drug candidates.

The ideal candidate will have a strong background in in-vitro and ex-vivo target validation and mechanism of action (MoA) interrogation across multiple cell types.

Responsibilities:

  • Independently design and execute experiments and studies to evaluate performance of investigative drugs (biologics)
  • Stay updated with cutting edge discoveries and trends and contribute to the company’s R&D strategy to generate and test actionable development plans
  • Identify emerging methods, tools, and biology approaches, and implement them when applicable
  • Function as a project and program leader and simultaneously mentor, train and supervise associates on the R&D team
  • Collaborate closely with other scientists and research associates on the R&D team
  • Contribute to work with external parties, including academic collaborators and CROs to create comprehensive capabilities for MoA, target validation and potency studies
  • Write clear and concise research reports and ensure study documentation and update protocols toELN
  • Participate and contribute to internal discussions and meetings
  • Present results to the project leadership team and management in an organized and timely manner

Your Background:

  • Ph.D. in Cellular Biology, Immunology, or a relevant discipline
  • 3-5 years of related industry research experience (including post-doc)
  • Extensive experience working with different types of in vitro systems such as immune cells, epithelial cells, fibroblasts, endothelial cells, and other cell lines- Strong background with cell based assays to interrogate immune pathway activation, immune suppression, cytotoxicity, antibody mediated cell killing
  • Broad skillset for target validation, potency evaluation and MoA interrogations is highly desired, including the use of tissue culture approach with multiple readouts, flow cytometry, ex-vivo studies, use of gene knockdown tools, conventional immunoassays, phosphorylation analysis and conventional pulldown assays

Benefits:

Competitive salary, plus bonus and health plans

Apply:

For more information please contact Hannah Oakley or Rob Angrave on +1 (617) 6922948. Please quote job reference 54215 in all correspondence.

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